Before we get to the esteemed Best Romantic Chemistry Tater Tops category, which is coming later this week, let's make a pit stop at platonic chemistry and discuss the TV friendships we love the most. (We're strictly talking canon here, so any slashy business happens on your own fanfic-writing time...)
Liz & Jack, 30 Rock: These two need each other to get through the workday like the rest of us need our morning Starbucks.
Serena & Blair, Gossip Girl: S and B are very possibly the OTP of Gossip Girl. They shop together, they talk together and they would fight to the death for each other.
House & Wilson, House: An inexplicable twosome, perhaps, but through Wilson's countless women and House's million neuroses, they carry on.
Shawn & Gus, Psych: Who wouldn't want to fight crime with their childhood best friend?
Sam & Dean, Supernatural: Yes, they're brothers first, but they're also each other's favorite people.
Who's your fave? Vote in the poll below!
Tater Tops 2009: Best Friends
Did we forget anybody you love? Post in the comments!