The TV stars were most recently seen relaxing at Mexico's St. Regis Punta Mita Resort from Feb. 12-15, just weeks after Meester reportedly had her bachelorette party at West Hollywood restaurant Hamburger Mary's.
The 27-year-old Gossip Girl star and the 34-year-old O.C. actor got engaged in November, just nine months after it was first revealed that they were an item. The famously private pair, who met on the set of 2011's The Oranges, have never officially confirmed they were a couple, nor did they confirm their engagement.
This is the first marriage for both stars. Meester previously dated actors Sebastian Stan and Aaron Himelstein, while Brody was linked to director Lorene Scafaria and dated his O.C. costar Rachel Bilson.
Meester makes her Broadway debut in Of Mice and Men this spring. Brody, meanwhile, next appears in the movie Think Like a Man Too. The newlyweds are both slated to star in the comedy Life Partners.
Us Weekly first reported the news of Meester and Brody's hush-hush marriage.