The 37-year-old actress took to her Twitter page to lash out at her American Pie pal after he not so kindly referred to her as a "hot mess" during an appearance two weeks ago on Bravo's Watch What Happens Live.
"@JasonBiggs it's really sad I just landed in LA and the first thing I read about you that you are calling me a hot mess.i I've supported you!" Reid tweeted after returning from a quick trip to Israel.
The Sharknado star's disappointment stemmed from a quip the 35-year-old funnyman said to host Andy Cohen when the latter asked the Orange is the New Black actor what prison nickname Biggs would give Reid—to which Jason offered up the unflattering description.
Biggs has so far yet to comment on the matter.
The two last worked together on 2012's American Reunion, the fourth installment in the American Pie movie series.
Biggs has been sticking with the small screen of late. Besides a short guest stint on CBS' The Good Wife last season, he's currently portraying a struggling writer engaged to a woman who's gone to prison on the Netflix original series.
As for Reid, after hitting the career skids in a slew of straight-to-video flicks, she's made a comeback of sorts in 2013's hit SyFy TV movie turned Twitter phenomenon, Sharknado. No word whether she'll be returning for the aptly titled sequel, Sharknado 2: The Second One.