"I certainly didn't realize how many people were dealing with this issue," Pitt told E! News' Alicia Quarles exclusively at last night's World War Z premiere in NYC, adding, "And so I'm really moved by it."
Jolie announced her decision back in May after finding out she carried the "'faulty gene" BRCA1 and had roughly an 87 percent risk of contracting breast cancer, something than many women with a family history of cancer encounter.
So does Pitt hope their six kids follow in his and Jolie's do-gooder ways? "That's quite a compliment, and I hope they would learn from that," he said to Quarles.
As for how the famous family recently celebrated Father's Day, Pitt said, "We do it big. We do big family things."
For more from Pitt, tune in to tonight's episode of E! News at 7 and 11:30 p.m.