Cast the jokes aside!
And not the feuding type of drama we're used to, either.
Deadline reports that Handler will take on the dark role of a restless housewife in the adaptation of Eric Bogosian's 2001 novel, Mall.
Handler's castmates include Law & Order: Criminal Intent star Vincent D'Onofrio, who plays a "voyeuristic businessman" and is also producing the film with partner Erika Hampson and Sam Maydew.
"This film will be a comment on social violence," D'Onofrio said in a statement. "It begins as a man walks through the front door of a suburban mall armed to the teeth, causing five strangers to embark on a night that will change them forever. As the bullets fly, one teenage boy hurtles through the night on a collision course with the man he will become."
Joe Hahn of Linkin Park will unleash his directing debut in this movie, and Bogosian will make a cameo as a store owner.
How do you think Chelsea will do? Sound off in the comments below!