The actor is in talks to come on board as a producer for the Warner Bros. film based on Armstrong's life, which will chronicle the cycling star's fall from grace after the athlete confessed to using performance-enhancing drugs to win the Tour de France.
E! News confirms the 38-year-old Silver Linings star is also looking to play one of the two major roles in the project, titled Red Blooded American, one of which is of course Armstrong and the other being Tyler Hamilton, Lance's former teammate and a member of his inner circle who famously said he saw the athlete doping in a 2011 60 Minutes segment.
So why do we think the former Sexiest Man Alive is perfect for the part?
Well, for starters, he looks mighty fine in a pair of biker shorts, and, turns out, the hunky actor is quite the avid cycler himself.
Cooper is a loyal fan of SoulCycle and has been spotted sweating it out in the popular cycling class on numerous occasions.
He's even been known to take two classes in a row (clearly, he likes a challenge!), and he loves to get his sweat on (he wore a sweatshirt and sweatpants to a recent class in Brentwood).
The SoulCycle stud also rides a motorcycle in his spare time, proving the Oscar-nominated actor is both an expert on a bike and the big screen, as evidenced by his highly-successful Hollywood career.
Cooper has previously expressed interest in playing the onetime sports hero, telling BBC News he would "love" to take on the role of Armstrong, "I think he's fascinating. What a fascinating character," he said.
The Warner Bros. project is one of at least three upcoming films based on the athlete's very public downfall.
J.J. Abrams is set to produce the Paramount Pictures biopic based on New York Times sportswriter Juliet Macur's book Cycle of Lies: The Fall of Lance Armstrong, while Ben Foster was recently in final talks to play the disgraced cyclist in an unnamed project produced by Working Title partners Tim Bevan and Eric Fellner.
Do you think Cooper is a good casting call? Tell us in the comments!