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    First Look! See Lady Gaga as La Chameleón in New Machete Kills Trailer

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    Lady Gaga is making her big-screen debut!

    In a newly released trailer for Machete Kills, the "Born This Way" singer is trying her hand at some fierce movie star acting.

    In the video, we get a brief glimpse of Gaga playing the character La Chameleón in Robert Rodriguez's upcoming sequel to Machete.

    WATCH: See Jennifer Aniston strip in new movie trailer

    The 27-year-old Grammy winner is seen sporting a fur shawl while trying to catch a ride alongside a busy highway.

    In addition to star Danny Trejo's badass moves, lots of knives and of course explosions, the clip also gives up a first look at some of the action flick's other stars, including Amber Heard, Sofía Vergara, Antonio Banderas and Michelle Rodriguez.

    Machete Kills hits theaters Sept. 13.

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    What do you think of the movie trailer? Sound off below.

    PHOTOS: Check out Gaga's crazy fashions

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