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    First Look! See Lady Gaga as La Chameleón in New Machete Kills Trailer

    Lady Gaga is making her big-screen debut!

    In a newly released trailer for Machete Kills, the "Born This Way" singer is trying her hand at some fierce movie star acting.

    In the video, we get a brief glimpse of Gaga playing the character La Chameleón in Robert Rodriguez's upcoming sequel to Machete.

    WATCH: See Jennifer Aniston strip in new movie trailer

    The 27-year-old Grammy winner is seen sporting a fur shawl while trying to catch a ride alongside a busy highway.

    In addition to star Danny Trejo's badass moves, lots of knives and of course explosions, the clip also gives up a first look at some of the action flick's other stars, including Amber Heard, Sofía Vergara, Antonio Banderas and Michelle Rodriguez.

    Machete Kills hits theaters Sept. 13.

    What do you think of the movie trailer? Sound off below.

    PHOTOS: Check out Gaga's crazy fashions

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