Argo won the Oscar for Best Motion Picture tonight.
With envelope in hand, the first lady of the United States announced the drama won its third award of the night.
"I want to thank you for working on our marriage," Affleck said. "It's work but it's the best kind of work and there's no one I'd rather work with."
Getting emotional, the 40-year-old also shared important lessons he has learned from his peers in Hollywood.
"You have to work harder than you think you possibly can," Affleck said. "It doesn't matter how you get knocked down in life because that's going to happen. All that matters is you have to get up."
Affleck couldn't end his thank you speech without a precious shout out to his three young kids who continued the tradition of writing heart-felt messages on his hands. "Violet, Sam and Seraphina, I love you," he said. "This is for you."