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Eric Dane, Grey's Anatomy

Randy Holmes/ABC

Spoiler alert! Something tragic and shocking (a few somethings, actually) happened on this week's season premiere of Grey's Anatomy, and if you haven't heard, then you don't have a heart. And that's the real tragedy here. 

Either way, we've got the inside dish on the latest Grey's death and dismemberment here, and a little solace: This is hardly the first time the sudsy-fun of Grace Hospital turned super tragic.

As a special tribute to [SPOILER!] and [SPOILER!], let's give it up for the show's biggest, jaw-droppingest, OMGest moments. Check it out. 

(Except if you don’t want to be spoiled!)