"I feel like such a heavy weight has been lifted off my shoulders," she admitted on Monday's E! News to longtime friend and co-anchor Ryan Seacrest, whom she had just shared the news with last night. "I've been keeping this secret from a lot of dear friends for a while now and it's nice to get it out there and not hide anymore."
Via satellite from New York, Rancic admitted that the decision to go public "was a difficult one." But once the celeb thought about all the women she could inspire and perhaps educate—regular breast exams are a must, ladies!—she knew there was nowhere to go but in front of the cameras.