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Rick Sanchez, Jon Stewart, Jessica Simpson, John Mayer, Kathy Griffin, Bristol Palin
Best of 2010 tile

Hollywood just wouldn't be any fun without a fiery feud from time to time, right?

And 2010 has been a great year for A-list smackdowns, too: pop stars and presidents going at it, comics tossing four-letter words at movie stars, cable news blowhards piling on everybody, and everybody piling on the Palins.

So as part of our month-long Best of 2010 melee, we look back at the celebrity scraps that did the most damage—and only one involved Kanye West!