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Hugh Laurie, James Gandolfini, House, The Sopranos

Trae Patton/FOX, Barry Wetcher/HBO

Don't mess with these guys. Seriously...except maybe that blond lawyer. All week, E! Online's TV Diva, Kristin Veitch, calls her picks and predictions for winners, so now let's try dramatic actors:

The Incumbent:  Kiefer Sutherland, 24

The Contenders

  • James Gandolfini, The Sopranos
  • Hugh Laurie, House
  • Denis Leary, Rescue Me
  • James Spader, Boston Legal
  • Kiefer Sutherland, 24

Who Should Win:  Hugh Laurie, House

Who Will Win:  James Gandolfini, The Sopranos

In one of this year's toughest categories, it's a no-holds-barred brawl for the small screen's heavyweight acting champions. Gregory House, M.D., will stand the test of time as one of television's most challenging, charismatic characters, but Tony Soprano, a fellow citizen of New Jersey, is nothing less than an American icon. Denis Leary and Kiefer Sutherland are also stellar actors, and James Spader is an Emmy favorite.

But through it all, put your money on Gandolfini.