Large families are almost always a little dysfunctional—or in the case of August: Osage County, a lot dysfunctional.

The upcoming comedy-drama (in theaters Nov. 8), based on the Tracy Letts' Pulitzer Prize-winning play and produced by George Clooney and Grant Heslov focuses on an Oklahoma family whose unpleasant matriarch, Violet Weston (Meryl Streep), suffers from mouth cancer and is addicted to pills.

And the latest trailer from the film gives viewers a closer glimpse at the flawed family.

August Osage County, Meryl Streep, Julia Roberts

Although the onscreen brood experience their fair share of turmoil, there are also moments—like struggling with saying grace at the dinner table or confusing the word "fear" with "farts"—that bring them together.

The film has an all-star cast that includes Julia Roberts, Ewan McGregor, Benedict Cumberbatch, Chris Cooper, Sam Shepard, Abigail Breslin, Juliette Lewis, and Dermot Mulroney, and has already gained Oscar buzz after premiering at the Toronto Film Festival.

Drew McWeeny from Hitflix praised Streep and Roberts, saying, "Streep is often both touching and terrible as Violet's drug-induced fog rolls in, leaving her fuzzy and disoriented, then rolls out again, allowing her to perform ego surgery on each of her kids, with remarkable accuracy. Roberts rarely chooses to play characters who are this openly angry and hard to like, and I have to say…she gives it everything she's got."

Watch the latest trailer from the film and tell us what you think!

PHOTOS: Movies from the future!

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