The groundbreaking movie follows the couple's love story from three different persepctives: hers, his, and theirs.
The first trailer for the romantic drama was just released and is quickly starting some serious early Oscar buzz.
Ned Benson, who directed and wrote the film, shot three totally different films and will release all three at separate times.
This also marks Benson's first feature film project.
The Disappearance of Eleanor Rigby: Them will hit the big screens on Sept. 26, with the other two versions being released later in the fall.
The highly anticipated film also stars Bill Hader, Viola Davis and William Hurt and was first debuted as a work in progress at the 2013 Toronto International Film Festival. It then later premiered at the 2014 Cannes Film Festival back in May.
E! News recently caught up with the redheaded beauty, who told us, "We made it for very little money, very quickly in the streets of New York and it was heaven. Absolutely."
She added, "The memories of why you want to be an actor with your friends, everyone loved each other, my best friend Jess Weixler is in it! It was like a dream come true being on set with everyone I love."