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Chelsea Handler Calls David Letterman a "Small Man" on The Late Show

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Leave it to Chelsea Handler to bust David Letterman's chops on his own show.

After Letterman asked Handler what she thought about the late-night landscape, the funny gal said, "It's a hot mess. No one can keep their job for very long it seems. You're lucky to be here at CBS."

And then she went in for the kill.

WATCH: Conan O' Brien and Chelsea Handler get into a naked shower fight!

When Letterman went on to say he would be lucky to have any job--even if it were mowing lawns--Handler quipped with a laugh, "well…you're a small man."

After admitting he was still stinging from Handler's "small man" comment later in her interview, Handler elaborated, saying, "You're not particularly large. You're very dainty for a man, and I mean that in the nicest way possible. I mean…you're fit."

WATCH: The Kardashians tear into Chelsea Handler on After Lately season finale

"You're kind of hefty for a broad," Letterman joked back.

Letterman isn't the only late-night host E!'s own Chelsea Lately host has smacked down, though.

The comedienne recently got into a nude shower fight with Conan O' Brien as well, after O'Brien showed up to bicker about her studio set—which he said used to be his. 

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Check out some of the stars who have showed up on Chelsea Lately!

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