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It's hard to believe that in less than one week, Giuliana Rancic will step foot on the E! News set as a co-anchor for the last time.

And to honor her decade at the post, we're taking a lengthy look back at some of the most memorable moments—all of the highs and the lows—that Giuliana has let us be a part of.

Between meeting her now-husband, Bill Rancic, to their fairytale engagement and wedding on the island of Capri, these two let viewers into their love story, no holds barred.

Giuliana also opened up to the cameras about her brave battle with breast cancer, as well as her infertility issues over the years.

But luckily, Giuliana and Bill's luck turn right-side up when the two welcomed their adorable son Duke into the world in August 2012.

But enough from us, take a look back at all of the many milestone moments from the red carpet star.

And fret not, there's more! Check out our mash-up below to see some of the funniest Giuliana faces over the years (Spoiler alert: There's a hair flip involved.)

Be sure to tune into ENews all this week at 7 p.m. and 11 p.m. to look back at our favorite moments with Giuliana!