This is definitely no laughing matter.

Shelley Malil, an Indian comedic actor best known for appearing in The 40-Year-Old Virgin, has been arrested on suspicion of attempted murder, mayhem and burglary after allegedly brutally stabbing an ex-girlfriend 20 times and then fleeing the scene.

The woman, who has not been identified, was listed in critical condition at Palomar Hospital Monday. Her current condition was not immediately known, though she is expected to survive the attack.

"Malil and the victim apparently had been in a dating relationship which recently ended," a statement released by authorities said.

The 43-year-old actor, who has also appeared in Scrubs, Seinfeld and NYPD Blue, was arrested after deboarding a train in Oceanside, Calif., around 6 p.m. Monday.

Malil had taken the train from Los Angeles in order to meet with his attorney, who had reportedly encouraged the actor, along with family and friends, to turn himself in to authorities.

The incident took place just before 9 p.m. Sunday at the victim's home in San Marcos. Deputies of the San Diego Sheriff's Department appeared on the scene after receiving reports of a woman screaming and hearing the shattering of glass.

Officials told San Diego's NBC affiliate, KNSD-TV, that Malil arrived at the home and found his ex-girlfriend in her backyard with another man, when he suddenly grabbed a knife and began stabbing her, subsequently chasing her through her home. When the unidentified male companion attempted to intervene, he was also stabbed in the hand.

Neighbors told the station the victim is the mother of two children, both of whom were home at the time of the attack.

"Her chin was almost entirely cut off," neighbor Charleton Lee, who rushed to her aid and attempted to stop the bleeding, told KNSD. "She had a huge gash in her arm that looked like a really deep wound that was bleeding profusely."

When deputies arrived, they found the woman with multiple stab wounds and cuts on her face, but Malil had since fled the scene.

Malil, meanwhile, has since been booked into the San Diego County Detention Center. Neither he nor his lawyer have issued any statement on the matter.

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