So did Chelsea Handler go after Angelina Jolie because Jennifer Aniston is Chelsea's new BFF?

Not quite.

"I'm been making fun of Angelina Jolie since she made out with her brother," the funnylady asserts on Chelsea Lately tonight.

Jolie was the target of Handler's snarky stand-up at a comedy show in Newark over the weekend, going so far as to use the C-word to describe the "homewrecker."

Tonight, she says it's simply funny business as usual, noting that Angelina has been a favorite target for five years.

"That should tell you that you should get some new material," comedian and round-table member Josh Wolf humorously replies. "Maybe it's time for a new joke."

"It's true!" Chelsea laughs. "If I've learned nothing from this, it's to write some new jokes."

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