Mark Salling & Chord Overstreet
Whether they're working on Glee or out on the town, we're glad these two hot young TV stars are bromantically involved.
Paul Rudd & Jon Hamm
The key to a long-lasting friendship may be early humiliation. That's how it was for the Knocked Up star, who has said that high school senior (and teenage romantic rival) Hamm was "super handsome, really smart, and very good at sports — all of these things that I most certainly was not."
Kanye West & Jay-Z
It's a good thing for everyone when longtime friends like Kanye and Jay-Z join forces to make records like Watch the Throne.
Tom Felton & Rupert Grint
We love it when our favorite celebs show up to support their pals! Rupert wears his heart on his chest for Tom at the premiere of Rise of the Planet of the Apes. Too adorable.
Vince Vaughn & Jon Favreau
Vince's latest flick is The Dilemma, but there's no dilemma when it comes to his friendship with Favreau. The on- and offscreen buds have been BFF since they met on the set of a flick back in 1993.
Seth Rogen & Judd Apatow
From Freaks and Geeks to Knocked Up to Pineapple Express, the actor and the director have worked on no less than 11 projects together. And Seth has said, "I couldn't say enough great things about him. He's the reason I'm not a homeless crackhead right now." Awww.
Robert Downey Jr., Guy Richie & Jude Law
The threesome had so much fun working on the first Sherlock Holmes movie they reunited for the sequel. And the timing couldn't be better when this three-way friendship formed—Guy leaned on his pals while his marriage to Madonna fell apart.
Zachary Quinto & Chris Pine
Whether jogging together or hitting film fest afterparties, it just warms our hearts to see these two Star Trek hotties are as much buddies offscreen as they are in the movie.
Ryan Seacrest & Simon Cowell
They may pretend to have a love-hate banter on American Idol, but Ryan actually called his colleague "one of the sweetest guys that you're ever going to meet." Yeah, seriously.
John Legend & Tom Colicchio
Music and food go together just as well as these two! When they teamed up for a Pairings event with American Express, the Top Chef judge refused to pick up his guitar (yep, he plays!) and perform with the "Ordinary People" crooner, but the talented duo totally teamed up to create a 55-track playlist for the evening.
Chace Crawford & Ed Westwick
The 411 has it that these Gossip Girl costars still share a true on- and offscreen bromantic love, even though they've moved out of their smelly apartment!
Robert Downey Jr. & Jake Gyllenhaal
The stars align when these Zodiac costars get together.
Tom Cruise & David Beckham
Who doesn't get a kick out of these two Top Gun-caliber cuties spending QT together?
Zac Efron & Leonardo DiCaprio
Yeah, yeah. We know Leo should be included here with any number of his actual pals—like Tobey Maguire or Kevin Connolly—but we prefer the fantasy of two generations of heartthrobs hangin'.
George Clooney & Brad Pitt
These Ocean's men always appear to be having a ball together at work or at play.
Corey Feldman & Corey Haim
The Lost Boys stars found each other while making that vampire flick and formed a bond that would see them through several more movies and even a reality show.
Sadly, Haim passed away in March 2010.
Lance Armstrong & Matthew McConaughey
These two buff beach babes "Live Strong"-er together than apart.
Ben Affleck & Matt Damon
This Oscar-winning pair set the standard for successful dude duos way back when.
Justin Timberlake & Trace Ayala
Creative collaborations seem to be at the forefront of most of J.T.'s friendships. His William Rast clothing line copilot is no exception.