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George Clooney was Danny Ocean, the leader of a band of thieves in Ocean's Eleven (and the two sequels that followed). His character was charming, handsome and had a mind brilliant enough to rob the Bellagio Hotel & Casino.
If you love to laugh and want to see Clooney dressed as Caesar only to get kidnapped while in costume then you should watch Hail, Caesar! ASAP.
The actor played himself in the hilarious Christmas TV special starring Bill Murray.
The Kentucky native played former boy-genius inventor Frank Walker in the 2015 film who goes on a mission with a young teen to uncover the secrets of a place that only exists in their memory.
In Gravity, Clooney (as Matt Kowalski) is the only person tethered to Sandra Bullock's character Ryan Stone as the two are lost in space.
Clooney wrote, directed and starred in the iconic film about a World War II platoon that is sent to retrieve masterpieces from the Nazis and return them to their rightful owners.
Clooney starred alongside Jennifer Lopez in the 1998 crime drama as bank robber Jack Foley.
In case you forgot, Clooney played Batman AKA Bruce Wayne in the 1997 hero flick and we'll always love him for it.
The Facts of Life was the actor's first real TV gig. He played the boarding school's neighbor, George Burnett, in 17 episodes of the hit comedy beginning in 1985.
As he waits for his final assignment as an assassin, Clooney's Jack starts to make friends in Italy and fall in love, which could jeopardize his safety.
Clooney played producer Fred Friendly in the 2005 film which was a biography about bringing down Senator Joseph McCarthy in the 1950s.
The Ides of March earned Clooney another Oscar nomination for his screenplay, but fans remember him as Governor Mike Morris who is running for president in the film which also starred Ryan Gosling.
Syriana earned Clooney his first and only Oscar. The film was loosely based on former Central Intelligence Agency agent Robert Baer and his memoirs from the Middle East and Clooney brought a version of him as Bob Barnes to life.
In the 2008 film, a disk containing secret information gets into the hands of two people at the gym who will try anything to sell it. Clooney plays Harry, a marshal at the State Department who is cheating on his wife.
Clooney's Ryan Bingham loves traveling and firing people for a living, but his travel lifestyle and frequent flyer miles are threatened when he meets a woman who flies as much as him, and has to deal with a new hire.
The actor portrayed Lyn Cassady in this 2009 film, who claims to be a former member of the U.S. Army's New Earth Army. He tries to convince a reporter in Iraq that his unit employs paranormal powers in their missions.
ER was the actor' biggest TV role to date and one of his most memorable characters of all time. He played Dr. Doug Ross for five seasons returning only when Julianna Margulies left the show (to tie up her storyline) and again on the series finale.
Archie Gates (Clooney) and three other soldiers set out to steal gold after the Persian Gulf War that was originally stolen from Kuwait. On their journey they discover people who need their help and must rise to the challenge.
Clooney was only on one episode of Friends, but fans still remember his cameo. He appeared as a doctor alongside his fellow ER co-star Noah Wyle in a 1995 episode and after treating Rachel (who was pretending to be Monica) they all went out on a date.
The Oscar-winning film follows Matt King (Clooney) as he tries to reconnect with his daughters—one of which is played by Shailene Woodley—after his wife gets into an accident. Meanwhile he's trying to sell his land in Kauai and figure out what's next.
Set in 1925, Leatherheads focuses on a brash football hero named Dodge Connolly (Clooney) as he tries to get his team from being a group of bar brawlers and losers to a united, winning team.
From 1988 to 1991 Clooney played Booker Brooks on Roseanne. He was the supervisor at the plastic factory and a total dreamboat.
Dr. Chris Kelvin (played by Clooney) is set to investigate the crew of a research station orbiting a bizarre planet, but when he arrives part of the team is missing.