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Sony Pictures/Kobal/Shutterstock, Michael Kovac/Getty Images for Lionsgate
The Roommate served as the Friday Night Lights star's first leading role in a movie as protagonist Sara. The same year the film was released, the 40-year-old actress led the Charlie's Angels series, which was canceled by ABC after just four episodes.
Kelly went on to appear in Just Go With It and The Butler, while also enjoying guest appearances on Parenthood, Jane the Virgin and Legends of Tomorrow. She currently stars on Titans as the DC Comics superhero Dove.
After high-profile romances with Chris Evans and Jesse Williams, Kelly is now dating The Daily Show host Trevor Noah, with a source telling E! News the pair is "very much in love."