John Goodman returns as patriarch Dan Conner.
Laurie Metcalf, who was the only performer nominated for an Emmy for the Roseanne revival, returns as Aunt Jackie in The Conners.
Lecy Goranson is back as Becky Conner. She originally handed off the role to Sarah Chalke to attend college during the original run of Roseanne.
Sara Gilbert returns as Darlene Conner in front of the camera and as an executive producer on the series.
Michael Fishman returns as the youngest Conner sibling, DJ Conner.
Maya Lynne Robinson joins the cast as Geena Williams-Conner, DJ's wife who returns from active duty.
Shameless star Emma Kenney will once again play Harris, Darlene's daughter.
Ames McNamara returns as Mark, Darlene's gender non-conforming son.
Jayden Rey is back as Mary, DJ's daughter and Dan's granddaughter.
ABC's The Conners stars Maya Lynne Robinson as Geena Williams-Conner, Jayden Rey as Mary, Michael Fishman as D.J. Conner, John Goodman as Dan Conner, Laurie Metcalf as Jackie Harris, Sara Gilbert as Darlene Conner, Emma Kenney as Harris, Ames McNamara as Mark, and Lecy Goranson as Becky Conner.