The actor picked up a Golden Globe and an Oscar nomination for his work as playing Charlie and Donald Kaufman in the 2002 film.
The star portrayed Alred and Frederick Borden in the 2006 Academy Award-nominated film.
The Golden Globe winner played lead twins Bill and Brady Kincaid in the 2009 picture.
The actor took home a British Independent Film Award for his work as gangsters Reggie and Ron Kray in the 2015 crime indie.
The New York native played Paul and Eli Sunday in the 2007 Oscar-winning film.
The former Saturday Night Live star played estranged twins Kevin Pope and Jake Hayes in the 2002 action comedy.
The English actor showed his fun side when he played Tweedledee and Tweedledum in Disney's 2010 live-action remake.
The star won an Emmy for her portrayal of Sarah Manning and her many sestras (aka clones) in the BBC America show.
The two-time Academy Award winner played sisters Margaret DeLorca and Edith Phillips in the 1964 thriller.
The Nickelodeon star played twins Sam and Melanie Puckett in two episodes, ttled "itwin" and "#twinfection."
The TV star put his acting abilities to the test as Luke and Mark on the Fox crime series.
The actor played Bobby and John Saint in Marvel's 2004 action film.
The Academy Award-winning actor played Jiff and Kit Ramsey in the 1999 comedy.
The actor played Jake Sully and his deceased twin brother in the 2009 blockbuster.
The Academy Award-winning actress took on the roles of Susan Evers and Sharon McKendrick in the original version of the 1961 classic film.
The Academy Award-winning actor played Beverly and Elliot Mantle in the 1988 picture.