This 2009 comedy finds Friends alum Matthew Perry given a chance to relive a pivotal moment in his life when he's turned back into his 17-year-old self, as portrayed by High School Musical's Zac Efron. Think It's a Wonderful Life meets Big in reverse.
So what if Lindsay Lohan has become a tabloid drama queen? Her performance as the teenager who ends up swapping bodies with her much stressed-out mother (Jamie Lee Curtis) ranks as one of her finest big-screen moments.
Kirk Cameron, the former Growing Pains star turned Bible thumper tag-teamed with Dudley Moore in Like Father Like Son, a male version of Freaky Friday. The body-switching MacGuffin here? A brain transference serum. (Et tu, Kirk?)
Before she found love in Wedding Crashers, Rachel McAdams had to put up with SNL vet Rob Schneider in this 2002 comedy. McAdams plays a cheerleader who tries on an enchanted earring only to find herself trapped in the body of a career criminal. A lame excuse to see Schneider in drag? Perhaps.
Body switching entered the action realm with John Woo's 1997 blockbuster hit, which saw John Travolta's good-guy FBI agent Sean Archer trade faces with Nicolas Cage's maniacal villain Castor Troy in an epic duel to the death. Watching both actors mimic each other to perfection is worth the price of admission.
The ultimate body swap: John Cusack and Cameron Diaz play a couple in serious need of therapy who find a doorway on the 7½ floor of the former's office building...which leads to John Malkovich's brain. Only Oscar-winning screenwriter Charlie Kaufman could come up with a story so perversely entertaining, it persuaded Malkovich to go along for the ride.
David Lynch gives the oft-used concept a sexy, metaphysical spin in his Möbius strip of a noir. Naomi Watts and Laura Harring swap more than just bodies in what is one of the steamiest lesbian encounters ever put to celluloid.
A female take on Big, Jennifer Garner plays a 13-year-old girl who wishes she were 30 only to wake up 17 years later a successful magazine editor. Rip Van Winkle never felt so fashionable!
As the voices of Donkey and Puss in Boots, Eddie Murphy and Antonio Banderas fall under the spell of Merlin the magician and end up switching cartoon bodies. It's up to Shrek to save them.
Trading places with your older self never sounded like fun. That is, until we saw Tom Hanks step into his now classic role as a grown-up Josh Baskin in Penny Marshall's 1988 comedy gem. And his performance of "Heart and Soul" with Robert Loggia at FAO Schwartz is priceless.
Done reminiscing? Time travel on over to our Movies From the Future gallery!