Harry Connick Jr.
The former American Idol judge headed to NBC to host, Harry, which is part talk show and part musical variety series.
Robert Irvine
The chef and restaurant repair man has a daily talk show on the CW aptly called The Robert Irvine Show, where he gives advice on life's toughest issues.
Mo'Nique
From 2009 to 2011, the comedian and Oscar winner hosted her own BET show, which featured a variety of guests and musical performances.
Bonnie Hunt
The Bonnie Hunt Show aired on CBS from 2008 to 2010. Modeled after Ellen, it featured an opening monologue and a variety of celebrity guests.
Kris Jenner
In addition to starring on Keeping Up With the Kardashians, the momager had her own show, Kris, which lasted only one season.
Khloe Kardashian
Kris isn't the only Kardashian to venture into the world of talk show hosting. Khloe also hosted her own show, Kocktails with Khloe, for a short time on FYI.
Fran Drescher
The Nanny star hosted her own talk show through Fox. Unfortunately, it only lasted 12 episodes before being taken off the air.
Caroline Rhea
Hilda Spellman hosted The Caroline Rhea Show for a brief time, following the end of Rosie O'Donnell's show and before being replaced by Ellen DeGeneres.