Monica was always meant to end up with Chandler, but that didn't stop us from loving her and Tom Selleck together.
Let's face it, we all have a crush on Beyonce Pad Thai, aka Mindy Kaling on the Hulu comedy.
Never forget the strip tease he did for Mindy. NEVER.
Even though we first met him in the middle of disaster covered in dirt, he was still the hottest plane crash victim ever.
Despite that Caesar haircut, Clooney was still sexy as hell.
Matthew McConaughey saved the day and rescued Jennifer Lopez from a runaway dumpster. Oh, and he also smelled like grilled cheese, according to her.
We tragically lost Patrick Dempsey's character last season, but we shall never forget those dreamy eyes, that dreamy hair and that oh-so-dreamy smile. No wonder they called him McDreamy.
The one, the only, the original....Ellen Pompeo will always be our person.
First came McDreamy, and then came McSteamy! Eric Dane was so insanely attractive that the scars from watching his untimely death still hasn't healed.
Sandra Oh is beautiful, but her sassy, smart personality makes her a total ten.
What do they put in the water up there in Seattle? Jesse Williams, you can operate on us anytime.
There is never any shortage of hot docs at Seattle Grace Hospital, and newbie Giacomo Gianniotti is no exception.
Another beautiful doctor at Seattle Grace? Color us shocked. We'll be checking in forever just to be surrounded by Sara Ramirez and the rest of her colleagues.
It's no wonder Ashton Kutcher was crazy about Natalie Portman's character in this 2011 comedy. Look at her!
Sure, Peter Facinelli's character on the Showtime drama was kind of tool, he was a tool with a heart of gold. And also, a face that was super fun to look at.
She could rock a white lab coat with six-inch Manolos like nobody else, and listening to medical jargon was much sexier when you heard it in Eve Best's accent.
Before Glee was but a twinkle in his eye, Ryan Murphy blessedly brought us Julian McMahon as the sexiest plastic surgery in Miami.
Harry Connick, Jr.'s character in the iconic sitcom had a very dramatic relationship with Grace, but at least that meant we got to see lots of him on our small screen.
Smart, handsome and able to put up with House's crap? Omar Epps' character was one of the best reasons to tune into the Fox drama every week.
House was a total jerk, addicted to pain killers and loved to push around his employees and his patients. Then how come we were insanely attracted to him? Oh, that's right. Nobody can resist a seriously good-looking bad boy.
Olivia Wilde is one of the most beautiful creatures on this planet, so putting her in a lab coat was like putting gasoline on a fire.
This movie will make you want to dump Purell all over your body, but at least the gorgeous Kate Winslet is there to help you through.
She was a wee bit crazy and definitely high-maintenance, but no one could ever deny the gorgeous Sarah Chalke.