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The singer-songwriter announced her transition from male to female on social media in October 2017.
The glamour model documented her 2013 transition in a series of extremely popular Youtube videos.
Just a few weeks after coming out as transgender during an interview with Diane Sawyer, Caityln made her first appearance on the cover of Vanity Fair magazine.
The television personality and author has penned numerous best-selling books about her experiences as a transgender woman.
Matrix director penned a lengthy statement with local media announcing her transition.
One of the breakout stars of Orange is the New Black, Laverne became the first out transgender person to appear on the cover of Time in May 2014 for the magazine's "The Transgender Tipping Point" story.
Cher and the late Sonny Bono's son documented his transition in the 2011 film, Becoming Chaz.
The YouTube celebrity was just 14 years old when she was named the face of Clean & Clear's new digital ad campaign in March 2015 and landed her first reality show for TLC.
In May 2015, Hari became the first transgender model signed by powerhouse agency IMG for worldwide representation.
Lili was the first transgender woman to undergo sex reassignment surgery in the 1930s. The Danish Girl, a movie about her life starring Oscar winner Eddie Redmayne, is set to be released in November 2015.
After serving in the U.S. Army during WWII, Christine became a household name in the early 1950s after the New York Daily News published a front page story about her transition.
The supermodel was discovered while working at a McDonalds when she was just 17. Since then, she has gone on to walk runways for Marc Jacobs and Jean-Paul Gaultier and was the first trans model profiled by Vogue.
Before her retirement in 2007, Balian was ranked as one of Germany's all-time best competitive pole vaulters.
Lana and her brother Andrew—known in Hollywood as the Wachowskis—are the directors behind The Matrix franchise, Speed Racer, Cloud Atlas and most recently, Jupiter Ascending.
A member of the famous Arquette acting family, Alexis appeared in more than 50 films. A documentary about her transition, Alexis Arquette: She's My Brother, premiered at the Tribeca Film Festival in 2007.
After becoming a fixture in New York City's nightlife scene, Candis was cast as Billy Baldwin's mistress in ABC's Dirty Sexy Money, making her the first transgender actress to play a recurring transgender character on prime time television.
The British beauty modeled for Australian Vogue and Harper's Bazaar in the 1970s before appearing in the James Bond flick For Your Eyes Only and posing for Playboy in 1981.
The Brazilian stunner became the new face of haircare giant Redken in November 2014.
Isis was the first trans person to compete on America's Next Top Model during its tenth cycle in 2008.