"This president of all people is going to come after me?" she asked. "He picked the wrong redhead."
Jokes aside, the star revealed she has been getting daily death threats and is currently under investigation by the Secret Service.
At several points, Griffin became tearful as she reflected on the state of her career in light of the controversy. "I've had everybody turn on me and I just want to make people laugh," she said as her eyes welled up.
"I don't think I will have a career after this," she answered one reporter. "He broke me."
While she hasn't spoken with her former CNN colleague Anderson Cooper, she said the network's decision to cut ties with her was "hurtful."
Though the comedian does not take back her initial public apology, she also said that she will stand up for her first amendment rights. "I am teasing the president because this is America and you shouldn't have to die for it," she said.
As for the photograph itself, Griffin said she and photographer Tyler Shields put "about five minutes" of thought into it and did not receive any payment for it.
Her criminal attorney Dmitry Gorin added that there was never an intention to threaten anyone with the image.