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And I'm happy to report that their love is stronger than ever.
The Black Mass actor gave his wife a shout out last night while accepting the Desert Palm Achievement Award at the Palm Springs International Film Festival.
"I also have to thank my wife Amber for putting up with me, for living with all these characters, which can't be easy," he said, referring to his many film roles. "It's hard for me—it's got to be hard for her."
In November, Depp exclusively opened up to me about Heard.