The actress took to Instagram tonight to share her support for the actor and longtime friend, who is appearing for a live, in-studio interview with Today's Matt Lauer in Studio 1A Tuesday. A press release issued Monday said the 50-year-old actor "will make a revealing personal announcement."
"My heart hurts. Prayers for Charlie and his family," Locklear wrote with a photo of the pair together.
Her post comes after E! News learned from multiple sources that Sheen is HIV-positive. Reps for Sheen did not respond to E! News' request for comment.