Jennifer Aniston

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America, get ready to see many of your favorite celebs wear red noses for a great cause.

The charity Comic Relief and NBC are bringing to the United States for the first time the Red Nose Day charity campaign, which has been held in the United Kingdom for decades. On May 21, the network will air a TV fundraising special featuring more than 65 celebrities. Jennifer Aniston and the band Coldplay were among the stars announced on Thursday, joining the likes of Reese Witherspoon, Benedict Cumberbatch, The Voice coaches and the Today show stars.

The event will also feature many cast members from HBO's Game of Thrones, past and present, and from Netflix's Orange Is the New Black.

"Featuring great comedy, videos produced by Funny Or Die, incredible music performances and Hollywood's favorite stars, the benefit event will help 12 charity organizations lift children and young people out of poverty, in the U.S. and throughout the world," NBC said in a statement to E! News.

Red Nose Day has been marked in the United Kingdom since 1988 with a live telethon, benefitting the main British charity Comic Relief U.K., which helps raise money for the poor. Fake red noses are sold in stores to help the cause. In the United States, you'll find them at Walgreens and Duane Reade pharmacies for $1 each.

NBC has also released a special Red Nose Day app.

As of Thursday, the list of celebrities set to appear are (in alphabetical order):

Adam Levine

Anna Camp

Anna Kendrick

Benedict Cumberbatch

Bill Gates (and Melinda Gates)

Billy Eichner

Blake Shelton

Carson Daly

Chris Pine

Christina Aguilera

Red Nose Day, Christina Aguilera



Danny Pudi

Eddie Redmayne

Elizabeth Banks

Emily Blunt

Gwyneth Paltrow

Sir Ian McKellen

Jack Black

January Jones

Jeanne Tripplehorn

Jeff Goldblum

Jennifer Aniston

Jodie Foster

John Krasinski

John Michael Higgins

Julia Roberts

Julianne Moore

Laura Linney

Leslie Mann

Martin Short

Matt Lauer

Michelle Rodriguez

Naomi Campbell

Natalie Morales

Neil Patrick Harris

Red Nose Day, Neil Patrick Harris


Nick Offerman

Olivia Wilde

Orlando Bloom

Paul Rudd

Pharrell Williams

Reese Witherspoon


Rob Huebel

Sam Smith

Sean "P. Diddy" Combs

Sienna Miller

Simon Cowell

Stephen Merchant

Will Ferrell

Yvette Nicole Brown

Game of Thrones stars and alumni:

Alfie Allen (Theon Greyjoy / Reek)

Charlotte Hope (Myranda)

Emila Clarke (Daenerys Targaryen)

Iwan Rheon (Ramsay Bolton)

John Bradley (Samwell Tarly)

Kit Harington (Jon Snow)

Mark Addy (Robert Baratheon)

Nikolaj Coster-Waldau (Jaime Lannister)

Peter Dinklage (Tyrion Lannister)

Rose Leslie (Ygritte)

Thomas Brodie-Sangster (Jojen Reed)

 Orange Is the New Black cast:

Adrienne C. Moore (Cindy)

Dascha Polanco (Dayanara)

Jackie Cruz (Flaca)

Lea DeLaria (Big Boo)

Samira Wiley (Poussey)

Selenis Leyva (Gloria)

Yael Stone (Lorna Morello)

NBC's Red Nose Day special airs on May 21 at 8 p.m. ET.

(E! and NBC are part of the NBCUniversal family.)

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