Harold Ramis

Tasos Katopodis/Getty Images for The Second City

Hollywood is mourning the loss of Harold Ramis.

The famous comedy filmmaker, who is arguably best known for directing Groundhog Day and CaddyShack, passed away today at the age of 69.

According to a statement, the beloved writer died from complications related to autoimmune inflammatory vasculitis, a condition that he had suffered from for the past four years.

"His creativity, compassion, intelligence, humor and spirit will be missed by all who knew and loved him," the statement added.

Celebs have been taking to Twitter today to pay tribute to the beloved Analyze This director, whose noteworthy writing credits include National Lampoon's Animal House, Stripes and Ghostbusters. Here's what the stars are saying: 

Harold Ramis, Ghostbusters

Columbia Pictures

Dan Aykroyd: "Deeply saddened to hear of the passing of my brilliant, gifted, funny friend, co-writer/performer and teacher Harold Ramis. May he now get the answers he was always seeking."

Steve Carell "Harold Ramis. Funny, gracious, kind hearted. A joy to have known you."

Jon Cryer "Two words: Groundhog Day RIP Harold Ramis."

Ron Howard: "Harold Ramis RIP. no one could ever top him in terms of somehow being Cool & off-the-charts creative and incredibly kind & gracious." 

Justin Timberlake: "Caddyshack. Griswalds. Egon Spengler was always my favorite Ghostbuster. Genius. My condolences to Mr. Ramis's family. #RIPHaroldRamis."

PHOTOS: 2013 Fallen Stars

Ernie Hudson, Bill Murray, Dan Akroyd, Harold Ramis, Ghostbusters

Columbia Pictures

Rainn Wilson "Was honored to have gotten to work with Harold Ramis, the Buddha of Comedy. Brilliant, humble, radiant. We've lost an icon. #GroundhogDay"

Olivia Munn "RIP Harold Ramis"

Kat Dennings "Devastated about Harold Ramis…Groundhog Day is my favorite movie of all time. He made people happy and influenced so many, including me."

Jimmy Kimmel "'I collect spores, molds, and fungus' - condolences to the family and friends of the great Harold Ramis"

Julianne Hough "Very sad to hear that we lost Harold Ramis. Exceptionally talented, exceptionally kind."

Margaret Cho: "Harold Ramis, you, my first comedy crush. You came to my show in Chicago, I was humbled beyond words. My heart won't recover from this. #RIP

Jon Favreau "No no not Harold Ramis. Worked for him years ago. He was the real deal. Growing up, his work changed my life. He will be missed."

Ralph Macchio: "RIP Harold Ramis - A creator of often outrageous comedy yet always laced with heart. If u don't recognize his name. Look it up!"

Patton Oswalt: "No Harold Ramis, no comedy as we know it today. #RIPHaroldRamis"

Thomas Lennon: "Harold Ramis. One of the best ever."

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