Ellen DeGeneres, Khloe Kardashian, Alicia Keys

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Once again, in a time of tragedy Twitter has become a sounding board for thoughts, condolences and ways to give back.

"Text REDCROSS to 90999 to help Oklahoma tornado victims," tweeted Parks & Recreation star Adam Scott, providing the most nationally accessible means of aiding those affected by a mile-wide tornado that ripped through the Oklahoma City suburb of Moore this afternoon, killing at least 51 people.

"This storm has devastated the community that I grew up in," said homeboy Toby Keith in a statement. "I rode my bike through those neighborhoods. I have family and friends in Moore. My heart and prayers go to those that have lost so much. But Moore is strong and we will persevere. God be with you all."

"Pray for everyone devastated by these storms, but especially for those families in Moore, OK right now...God, wrap your arms around this community," Trisha Yearwood posted on her Facebook page.

"I just want to send my love to anyone who lives in the path of these storms. First Texas, now Oklahoma. You're all in our thoughts..," wrote Ellen DeGeneres.

And they were certainly not alone in their sentiments...

Alicia Keys: So much going on in the world...I'm saddened by the devastating news… My thoughts and prayers are with all those affected #PrayForOklahoma"

Khloé Kardashian Odom: "My heart is breaking for Oklahoma!!!! Please Lord please send your angels to heal and protect these families!!!"

Rosie O'Donnell: "Total Love and light to Oklahoma 51 gone 

Craig Ferguson "Tonight's show was taped last week so there's no mention of the terrible situation in Oklahoma. Sincere condolences to all affected."

Alyssa Milano: "To search for friends & family or to register yourself as safe from the #Oklahoma tornadoes: http://Safeandwell.org  via @10NewsCha @heykim"

Kristen Bell: "I just donated to Oklahoma Tornado Victims Fund via @ryotnews http://www.ryot.org/campaigns/oklahoma-tornado-victims-fund …"

Olivia Munn: "The devastation through my home state of Oklahoma is staggering. All of my prayers are w/the victims, especially all those little kids. XOX"

Slash: "Horrible what the people in Oklahoma just went thru. The devastation they're facing now. & the lives they've lost."

Kevin Smith: "Heartbreaking death toll in Oklahoma. Hug your loved ones close tonight and let's all get ready to help out OK in any way we can tomorrow."

Patton Oswalt: "Hunker down, Oklahoma. Sorry you're going through this. It's this random, wild planet. REDCROSS to 90999"

Neil Patrick Harris "I just can't believe the scale of that tornado that touched down in Moore. A mile wide?!? My condolences go out to everyone affected."

Jennifer Love Hewitt "My heart and prayers go out to everyone in Oklahoma. So tragic. Sending light."

Barbara Walters: "My heart goes out to Oklahoma tonight. Keeping you all in my thoughts."

Chelsea Clinton "Thoughts & prayers with Oklahoma."

Steve Austin: "Talked to @JRsBBQ today. He and his wife are ok. My thoughts are with all of Oklahoma. Total devastation by those tornadoes."

Floyd Mayweather: "My heart goes out to everyone feeling the impact of the tornadoes in the OKC area. Stay safe and #PrayForOklahoma."

John Rich: "I grew up in tornado alley. Amarillo,TX. There's nothing more terrifying than that "sound" bearing down on you. #prayforoklahoma"

Crystal Hefner: "Our thoughts go out to everyone in the Oklahoma City area tonight in the wake of today's devastating tornado. #PrayForOklahoma"

Jackée Harry: "Jacks & Jills, $10 Donations Can Be Made To The Red Cross Disaster Relief Fund By Texting The Word REDCROSS To 90999 #PrayForOklahoma RT!"

David Boreanaz: "Sending prayers to the people of Oklahoma."

Rob Thomas: "Please send thoughts, prayers, blood and donations to Oklahoma. Truly devastating and heartbreaking."

Solange Knowles "Oklahoma, you are in my thoughts..."

Evelyn Lozada: "24 children still missing in Oklahoma! There's a father on site crying looking for his 9 year old child! This is so not fair! Kiss ur kids!"

Sophia Bush "Heart breaking... RT @HuffingtonPost: Check here for live updates of the Oklahoma tornado devastation (LIVE BLOG) http://huff.to/19WOEih "

Mike Epps: "Prayers go out for the families in Oklahoma."

Dick Vitale: "Heart pains 4 all those that have been victims of those storms in Moore Oklahoma - that is the home of Toby Keith country star-#PRAYERS"

Jacqueline Laurita: "Sending prayers, love, support, and peace to Oklahoma. These natural disasters keep breaking my heart. XOXO!"

Ben Savage "My thoughts and prayers go out to the families affected by today's events in Oklahoma"

LeVar Burton "Praying for the Oklahoma families affected by the #tornado...!"

To make a $10 donation to American Red Cross Disaster Relief, text REDCROSS to 90999 (standard messaging rates apply)

(Originally published May 20, 2013, at 8:40 p.m. PT)

PHOTOS: Celebs giving back

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