Joe Biden, Paul Ryan, VP Debate

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Joe Biden and Paul Ryan showed up ready to rumble—and plenty of celebrities were ready to tweet all about it!

The Twitterverse was alive with the sounds of virtual whooping and hollering after tonight's vice-presidential debate, the only one scheduled between President Barack Obama's and Mitt Romney's running mates. (Obama and Romney go at it again on Tuesday in New York, by the way.)

And just as the presidential head-to-head had Hollywood all in dither, this war of words (like malarkey!) provoked extreme—and, in some cases, extremely hilarious—reactions from stars of all stripes. Here's a sampling:

Kevin Nealon: "Biden and Ryan could never work together as synchronized swimmers. #VPDebate."

Lisa Ling: "Good and feisty debate. Both represented their sides well."

Bill Maher: "Biden is hitting in one answer all the things Obama left out in the entire first 90 minute debate." 

Patton Oswalt"'The carved wooden doll across from my has gained sentience and wants to kill the country.' -- Biden's closing statement. #debate." And: "'The old man across from me is made from abortions lashed together with Ani DiFranco's public hair.' -- Ryan's closing statement #debate."

Bill Rancic: "Wow...what a battle we are watching tonight in this debate."

Eva Longoria: "Every channel declaring a Biden victory! Biden def delivered the facts tonight and held Ryan accountable for the lies! #TeamJoe"

Olivia Wilde"'@MiaFarrow: Biden kicked ass Ryan twerp I love you Martha Raddatz'. Word."

Samantha Bee: "I'm listening to the debate on the radio so I can't see anything. Biden's wearing leather pants, right? Please say yes."

Kat Dennings"Paul Ryan comes off like a 5 year old under a tree telling his friends what the rules of tag are #debate."

Chuck Woolery"Ryan now having to debate Martha too."

Caroline Manzo: "I feel like I'm watching a real housewife reunion as I watch the debate -"

Kenny Mayne: "Sad that the commentators marvel over fact debate was substantive."

Charlie Daniels: "I didn't see but a little bit of the debate but Biden came off as Condescending to me."

Kirstie Alley: "liking this debate!!!..... ruff!!!!!"

Lisa Rinna: "If you are not watching this debate right now you should its amazing!"

Greta Van Susteren: "Does this debate feel like a Chris Mathews show on crack?"

Meghan McCain"This debate is blood sport. Crossfire style. Don't know how this will change swing voters minds....enjoying Martha though."

Dane Cook"They need to play The Little Rascals theme music underneath this debate."

Roger Ebert: I vote for Martha Raddatz to moderate all the debates. #vpdebate."

Bethenny Frankel: "I can't watch this debate without thinking about these two candidates being mocked on SNL this Saturday."

Rob Lowe: "Was that a 'You're no Jack Kennedy' moment from Ryan?"

Lo Bosworth: "Joe, stop laughing. Your teefs are distracting me from the issues at hand!!!"

Sarah Hyland: "Paul Ryan's pin is bigger than Biden's.#debates #fact."

Eric Stonestreet: "Joe's laughing and smirking is probably going over as well with republicans as Paul's hairline is with democrats. #debates."

Elizabeth Reaser: "Need to party with Biden."

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