Robert Downey Jr. certainly knows a thing or two about overcoming a challenging past.  

So with speculation that Charlie Sheen's recent troubles may have been substance-related, what does the Iron Man star think is the key to successfully overcoming it? 

"It's different for everybody," Downey Jr. told E! News on Thursday night at the Hollywood premiere of his new movie Due Date. "The weird thing is that someone who's been through it is expected to talk about it. I'd rather just talk to them."

In fact, he wouldn't hesitate if his old pal decided to call him and wanted to chat about things.

"I'd like to talk to Charlie, he said. "I've known him for ages."

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