Michael C. Hall, Christina Appelgate, Lance Armstrong

Jon Kopaloff/Getty Images; Jason LaVeris/FilmMagic; Jason Merritt/FilmMagic

Stand Up to Cancer's megafundraising television event is going to be star-studded.

The telethon, taking place Sept. 10, will include a mix of Hollywood celebs, athletes and journalists...

Among the many who have signed on to appear are cancer survivors Christina Applegate, Lance Armstrong, Michael C. Hall, Maura Tierney, Robin Roberts, Marissa Jaret Winokur, Fran Drescher Survivor winner Ethan Zohn and Elizabeth Edwards.

Joining them for the big night will be Reese Witherspoon, Queen Latifah, Laura Linney, Seth Rogen, Sally Field, Terrence Howard and even the Simpsons.

Executive produced by Laura Ziskin, the program will be hosted by Katie Couric, Diane Sawyer and Brian Williams and will be telecast live without commercials on our very own E!, The Style Network and G4 as well as ABC, NBC, CBS, Fox and HBO, among other channels.


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