In Step Brothers, Will Ferrell and John C. Reilly play—you guessed it—40-year-old stepbrothers still living at home with the 'rents. When we sat down recently to chat, these two funny dudes let loose about how painful it can be making physical comedy. Plus, Ferrell offered a few tips on how to make it big with your own FunnyorDie.com. Hit the clip to get the full story.