The controversial comedienne went bald to show support for her sister Joyce Griffin, who's undergoing chemotherapy in her ongoing cancer battle.
The American Idol alum famously ditched her platinum blond waves in solidarity with her childhood best friend, Summer Holt Miller, who was diagnosed with breast cancer in 2012.
The former president touched many in 2013 when he shaved his head in support of a toddler battling leukemia, whose father was a member of Bush's Secret Service detail. Three years later, "41" shared a positive update on little Patrick's health.
In preparation for her role as a cancer-stricken Hazell Grace Lancaster in 2014's The Fault in Our Stars, the actress went for a chic pixie cut and donated her tresses to non-profit organization Children With Hair Loss.
One Direction's loyal followers were sent into a tizzy when the singer-songwriter said goodbye to his luscious brunette flow in the name of British charity Little Princess Trust, which provides wigs made from real hair for children who have experienced hair loss to cancer treatment.
Known for her waist-grazing, honeyed blond hair, the Mamma Mia! star shocked many when she debuted a sleek lob in 2015. Seyfried donated her tresses to Locks of Love, a charity that makes wigs for children suffering from conditions that cause permanent hair loss.
Bald and beautiful! Back in 2013, the British pop star shaved her head on live television in support of the Little Princess Trust.
Flying Tomato, no longer. In 2012, the professional snowboarder made waves when he took a pair of scissors to his fiery red curls in support of Locks of Love.
Short hair, don't care! The Jane the Virgin's raven locks went to Locks of Love in 2016, and she's maintained her cropped 'do ever since.
The R&B singer and mom-to-be recently went bald in honor of her child who is battling cancer.