Charlize Theron, Seth MacFarlane, Ellen

Michael Rozman/ Warner Bros.

This is one joke the GOP may not find funny.

Seth MacFarlane likes to call Charlize Theron's son Jackson "little Republican" and it's not exactly a compliment.

In an appearance on The Ellen DeGeneres Show, which airs Wednesday (May 21), the 40-year-old actor/producer/writer/director and the 38-year-old actress sat down to chat about their new western A Million Ways to Die in the West.

When Ellen DeGeneres asked about Theron's son Jackson, the actress replied, "He's great. He's great. You know, he pretty much he's just…I just scored big time. He's great. Seth calls him the little Republican."

The talk show host seemed a little confused and wanted to know why. So Theron offered up an impression of the precocious two-year-old.

"Cause he's just always saying no…'No, no, no, no, no, no...' Everything's no. No, no, no, no, no, no…No, Seth, no. Mama, no. No.' It's a lot of that."

MacFarlane got a good chuckle out of it.

BTW, A Million Ways to Die in the West hits theaters May 30, 2014.

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