Sara Ramirez, Madam Secretary

CBS

When Madam Secretary returns for its sixth and final season, it'll be down at least one cast member: Sara Ramirez.

The Grey's Anatomy veteran, who joined the cast in season four, will not return for the sixth season. At least not as a series regular.

According to The Salt Lake City Tribune, the final season of Madam Secretary jumps into the feature and Téa Leoni's Elizabeth McCord is no longer the secretary of state, but the president of the United States.

"We have not announced anything, but we are doing about a two-year time jump," Amy Reisenbach, the executive vice president of current affairs at CBS, told The Salt Lake Tribune. "When we come back, Elizabeth will be president. It will be about 100 days into her presidency."

That means Ramirez's political strategist isn't really needed since, well, the strategy worked. TVLine confirmed her exit. Ramirez hinted at the exit on Twitter.

"I know there's a lot going on in the world. So much," she shared. "And for just a quick moment I want to wish everyone at @MadamSecretary a fantastic final Season 6 @CBS! It was an honor to bring Kat Sandoval into your universe!"

See how other shows made their exits from hit shows below.

The Magicians, Jason Ralph

Syfy

Emily Bett Rickards, Arrow

CW

The Walking Dead

AMC

Nicollette Sheridan, Dynasty

CW

George Eads, MacGyver

CBS

The Walking Dead

AMC

Lethal Weapon, Damon Wayans

Fox

Shameless

Showtime

Brooklyn Nine-Nine

NBC

Emmy Rossum, Shameless

Showtime

The Walking Dead

AMC

Pauley Perrette, Mark Harmon, NCIS

Sonja Flemming/CBS

Arrow, Speedy, Willa Holland

CW

Grace Park, Hawaii Five-0

CBS

Daniel Dae Kim, Hawaii Five-0

CBS

Chicago PD, Sophia Bush

NBC

Silicon Valley, T.J. Miller

HBO

Erinn Hayes, Kevin Can Wait

CBS

Once Upon a Time, Season 6

ABC

Nashville, Connie Britton

ABC

Castle, Nathan Fillion, Stana Katic

ABC

Sleepy Hollow, Tom Mison, Nicole Behari

Tina Rowden/FOX

NCIS, Michael Weatherly

CBS

The Vampire Diaries, Nina Dobrev

The CW

Kal Penn, HOUSE

Greg Gayne/NBC/NBCU Photo Bank via Getty Images

Law & Order SVU, Christopher Meloni

NBC

Cote de Pablo, NCIS

CBS

Christopher Abbott, Girls

HBO

Kellie Martin, ER

Paul Drinkwater/NBCU Photo Bank

David Caruso, NYPD Blue

ABC Photo Archives/ABC via Getty Images

Michael Vartan, Alias

ABC

Michael Pitt, Boardwalk Empire

Macall B. Polay / HBO

Shannen Doherty, Charmed

WB

T.R. Knight, Katherine Heigl, Grey's Anatomy, Worst TV Couples

Vivian Zink/ABC

Dan Stevens, Downton Abbey

PBS

Josh Charles, The Good Wife

CBS

Teen Wolf, Crystal Reed

MTV

Colton Haynes, Arrow

The CW

Grey's Anatomy, Patrick Dempsey

ABC/Kelsey McNeal

The O.C., Mischa Barton

FOX

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