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Alexis Arquette's family is speaking out following the death of the Hollywood actress.

Hours after news broke of her passing, brother David Arquette headed to Twitter where he expressed his love and admiration for his sibling.

"Thank you all for your love and kind words about Alexis," he shared on social media. "My hero for eternity."

Soon after, Courteney Cox expressed her condolences to the family with a heartfelt message online.

"My heart goes out to anyone who was lucky enough to know Alexis," she wrote. "We will love and miss you forever."

On Sunday morning, Alexis' brother Richmond Arquette reportedly confirmed the news on his Facebook page writing, "Our brother Robert, who became our brother Alexis, who became our sister Alexis, passed this morning September 11 at 12:32 a.m. He was surrounded by all of his brothers and sisters, and one of his nieces and several other loved ones. We were playing music for him and he passed during David Bowie's Starman. As per his wishes, we cheered at the moment that he transitioned to another dimension."

Sister Patricia Arquette later tweeted, "To My first best friend - Cosmic Dancer. Breaking through the veil singing StarMan." 

Fans may remember Alexis from her roles in Last Exit to Brooklyn, Pulp Fiction and as a Boy George impersonator in The Wedding Singer. She also starred in Vh1's reality show titled The Surreal Life

The family asks that in lieu of flowers or gifts, fans can send donations to organizations that support the LGBTQ community in honor of Alexis. Our thoughts and prayers go out to her family during this difficult time.