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Joe Jonas, Neil Patrick Harris, Best Time Ever With Neil Patrick Harris

NBC

So many guest stars, so little time!

Neil Patrick Harris is about to welcome even more of his famous friends on Tuesday's episode of Best Time Ever With Neil Patrick Harris, his new hit NBC variety show.

E! News can exclusively reveal the line-up of guest stars that will be stopping by the Sept. 29 episode, including Tyler Perry as the latest guest announcer, taking over for previous announcers Reese Witherspoon and Alec Baldwin!

Oh, but wait, we're not done revealing Best Time Ever's celeb guests just yet: Olympian and Dancing With the Stars champ Apolo Ohno will introduce a new segment, "Ticket to  Slide," where one lucky couple will have the chance to win the trip of a lifetime when Apolo, who will appear throughout the series as a live correspondent, turns up in their city. Plus, CeeLo Green is set to headline this week's "Singalong Live." Substance Over Hype will perform in the "End of the Show Show," and Sister Sledge will make a special appearance on the show.

Previous guests on Best Time Ever include Britney Spears and Joe Jonas, who pranked bodyguards together, as well as The Voice coaches and Seth Meyers.

Best Time Ever airs Tuesdays at 10 p.m. on NBC.

(E! and NBC are both members of the NBCUniversal family.)

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