Fox's hit medical-mysteries series House is mixing it up next week, and you Wilson (Robert Sean Leonard) fans are going to love the twist!

Instead of Gregory House (Hugh Laurie) being the lead investigator on a health crisis, sidekick James "Jim" Wilson is the man at the center of the show, and Celebrity Jeopardy! standout/The West Wing star Josh Malina plays the patient who Wilson must save.

As executive producer Katie Jacobs told us earlier this year, "We have this upcoming episode where House is to Wilson as Wilson is usually to House. Like he'll be in the middle of something and House will drop by, or he'll go see House in the middle of a differential diagnosis meeting, and we'll never even know what they were working on. I'm excited about it."

For an exclusive sneak peek video of Robert Sean Leonard's star turn, which airs Nov. 30 at 8 p.m. on Fox, press play above!

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• Bones: Approximately 6 million years after we all started begging her, Zooey Deschanel is finally guest starring on her big sister Emily Deschanel's show, Bones. Zooey plays Brennan's wacky cousin Margaret in "The Goop in the Girl," which airs Thursday, Dec. 10. Can't wait! (Check out our TV Stunt Casting gallery for another shot of Zooey D.'s long-awaited TV gig.)

• Coming Soon: Fox just released the premiere dates for its midseason shows. Possibly unbelievably bad reincarnation drama Past Life premieres on Feb. 11, wait-and-see actioner Human Target premieres Jan. 17 (it has Mark Valley and Chi McBride, but still...), and probably totally cute comedy Sons of Tucson premieres March 14. Any thoughts from the peanut gallery on this trifecta?

• Lie To Me: Executive producer Shawn Ryan tweets, "#LieToMe picked up for a back 9! Thanks for all the support everyone!" Now, Q's for you LTM fans: (a) What do you love most about this show? and (b) What kind of scoop do you want on it, if any?

• The Oprah Winfrey Show: The times they are a-changin'. A Harpo Productions rep tells HuffPo that Oprah's not going to do a holiday "Favorite Things" episode this year. Madness!

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Click through our gallery of Oprah's Most Memorable Moments.

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OK, so apparently, all the TV networks simultaneously noticed Tuesday nights have been a bit of a dead zone in terms of hipster TV. Yes, CBS has lots of high-rated shows that night, and FX has had Sons of Anarchy, and ABC is trying its darnedest with V, but compared to the utter gridlock of Mondays and Thursdays, Tuesday TV has been blissfully low-stress when it comes to must-see shows.

No more. Fox just released its 2010 TV schedule and it has placed Glee's new episodes (which premiere April 13) on Tuesday at 9 p.m. Unfortunately, Tuesdays at 9 p.m. just so happen to be when ABC is putting the final season of Lost. Not to mention there are already plenty of Melrose Place, NCIS: L.A. and The Biggest Loser fans out of there, and their faves all already air at that time.

Brutal, man. Our house has four DVRs total, so we can probably survive this without picking up a third dual-tuner TiVo at Best Buy, but most people don't have such a gluttonous appetite for TV. Therefore: Choices must be made.

Take our poll below and then hit the comments with your thoughts.

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Hold on to your sofas, TV fans, because Wednesday night's 100th episode of Criminal Minds is going to be superscary! C. Thomas Howell is back as George "The Reaper" Foyet, and he's got Hotch's (Thomas Gibson) family in his evil clutches. Honestly, we're not sure that Haley (Meredith Monroe) is going to make it. Eek!

Click in to see J.J. (A.J. Cook) defend Hotch to that mean lady who runs the BAU division of the FBI along with other sneak peeks of Wednesday night's craziness!

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The Madonna episode of Glee is here! While babysitting Mr. Shu's wife's sister's brats, Quinn (Dianna Agron) and Puck (Mark Salling) make beautiful music together. To be specific, she sings and he accompanies a rendition of Madonna's 1980s teen-pregnancy classic "Papa Don't Preach."

Press play above to sing along, and then click in for your first look at guest star Eve as the choral coach of a continuation school for wayward girls...

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Can you believe we have to wait almost two months for a new episode of Supernatural, especially after yesterday's heartbreaker "Abandon All Hope"? The wait is going to be positively gruesome, but to keep, well, hope alive during the holidays, we gathered up the answers some of your burning SPN fan Q's.

So what's the biggest question of all right now in the Supernatural-verse? For our money it's this: Why is God so darn laissez-faire in his approach to the Apocalypse? The Winchesters could really use a hand mopping up all the fire and brimstone that's raining down on Earth right now! Come on, big man! Show your face!

So, will there be a deus ex machina in season five of Supernatural? Here's what we're hearing:

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• Lost: According to ABC, Lost season six will premiere Feb. 2 at 9 p.m., which means Tuesday is now Lost day. ABC also confirms that Nestor Carbonell's Richard Alpert, Ken Leung's Miles, Jeff Fahey's Frank Lapidus and Zuleikha Robinson's Ilana have all been upped to series regular status (we hear that Ilana has close personal ties to the Island); Emilie de Ravin is back full-time as Claire; and that Henry Ian Cusick's Desmond is not a season-six regular, although he'll no doubt appear as a heavily featured recurring character. In other Lost news, a little birdie tells us exclusively that the Lost season five DVD/Blu-ray packaging has hieroglyphics hidden within the cover art that offer additional clues to the nature of season six. (The hieroglyphics are not included in the promo artwork released so far.) The DVDs are due out Dec. 8, so make sure your local Egyptologist is on call that day!

Want to know about more good TV airing this winter? Read on for info on Chuck's return date and a surprise NBC pickup:

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We got taken for a ride by a Top cheftestant, and we don't mind one bit.

When we told you a couple weeks back that we had reason to believe that a front-runner (Jen, Kevin, Mike V. or Bryan) went home early, that reason was because someone from our team ran into "the red-haired guy from Top Chef" (aka Kevin Gillespie) while our friend was shopping for engagement rings in downtown L.A. The chef in question told our friend, "I got kicked off before the end." Well, as you saw last night, Kevin won the final Vegas challenge and sailed safely into the finale, along with fellow obvious finalists Jen Carroll and the Volt bros.

(FYI, this encounter happened in mid-October, which we believe to be before Kevin went north to shoot the finale in Napa, so don't sue us if Kevin doesn't make it into the final three and you feel spoiled. In that case, it's just a coincidence and we're not liable, darn it!)

We warned you at the time, "It could be part of a Bravo misinformation campaign, but we trust the source, so we're passing it along to you." Well, it's looking more and more like misinformation is the case, and we have to say, "Thanks, Bravo!"

Why are we grateful to have been taken for a ride? Well...

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Here's the bad news: Kim Raver's Teddy Altman is definitely a complication for Grey's Anatomy's most beloved twosome of the moment: Kevin McKidd's Owen Hunt and Sandra Oh's Cristina Yang. As Kevin McKidd correctly pointed out when we spoke earlier this week, "For a TV show to work, the characters can't be happy all the time." (Bah humbug!)

Now, here's the good news: McKidd and costar Oh are both total Crowen shippers who want to see their characters together as much or more than we do. McKidd testifies, "I want the best for him. I want him to be happy. I want him to be in love. I want him to be all these things, and so does Sandra [for her character]." And you've got to believe that all that love for love will win out in the end, right?

Kevin McKidd explained to us why he and Sandra are so in sync, both on- and offscreen, and what this triangle means for the show. Plus, McKidd revealed a worrisome suspicion that Owen's old nemesis might be back sooner rather than later...

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Tonight on So You Think You Can Dance we learned that while a remarkable solo can save a dancer in danger, a totally terrible solo won't necessarily get you sent home if you have already banked enough "star moments" and sex appeal in the minds of the judges.

We've got the scoop from behind the scenes at SYTYCD that reveals why a "very good" dancer went home in place of the dancer with one of the most unchoreographed and random solos in recent memory...

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Not So Horrible: In case you turned off the Internet yesterday, you may have missed the news that Neil Patrick Harris joined Twitter. NPH finds Twitter a fascinating and strange new medium for his comedy stylings. See above for proof.

Whee, Glee! New instant-classic Glee music is available online, including a version of "Lean on Me" (we're already preparing to cry during this TV performance), a fabulous pop "Crush," and "I'll Stand by You," which we have to guess (just guess) is Cory Monteith's Finn serenading Dianna Agron's Quinn about her pregnancy and such. Loverly!

Together Again? These new photos of Chace Crawford and Taylor Momsen filming Gossip Girl in New York remind us what a cute couple Little J and Nate were way back in season two. Anybody else want to see them rekindle something once Jenny turns 18?

Taking a Break: Julianne Hough told our own Ryan Seacrest she won't be back for Dancing With the Stars season 10.

American Music Awards: E! got the exclusive scoop that our girl Kristen Bell will be a presenter at the American Music Awards this weekend, along with Selena Gomez, Demi Lovato and Colbie Caillat.

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Click through our TV Celebrity Stunt Casting gallery for a sneak peek of James Van Der Beek on ABC's The Forgotten.

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Want to know which questions are most likely to be answered by the final hours of Lost, which direction Josh Holloway's Sawyer might be going (romantically and otherwise), and why we fans need to be wary of double-talking producer doubles?

Well, good news then! Lost boss Damon Lindelof and the rest of Bad Robot movie and TV mafia came out to party Monday night at the beautifully lit Griffith Observatory in Los Angeles, which was all decked out for the gala DVD/Blu-ray premiere of J.J. Abrams' Star Trek movie. And while the new Star Trek movie is straight awesome, we got so excited by all the TV talent present that we had to also ask them a few burning questions about the final season of Lost, which is set to premiere on ABC in just about two months.

The guys were kind enough to put up with our inquiries, and we're sharing the scoop they spilled about your burning questions...

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