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Sun., Oct. 4, 2009 3:10 PM PDT by Brandi Fowler and Lindsay Miller

The big 4-0 never looked better.

Gwen Stefani celebrated the advent of her fourth decade with friends and family at an intimate Saturday afternoon gathering at Cecconi's in West Hollywood.

The ab-flaunting singer donned her signature red lipstick as she dined inside the Italian restaurant with hubby Gavin Rossdale, sons Zuma and Kingston, BFF to the stars Kate Beckinsale and the actress's husband, director Len Wiseman.

"There wasn't much gift-giving, but they did bring in a large bouquet of red roses, and as they were leaving, they stuffed some Mylar balloons in the backseat," an eyewitness told E! News

"They are such a class act. They were so gracious with all of the photographers, and Gavin was even joking around, waving and taking pictures on his iPhone as they left," says the source. "I think they chose to have the party in the afternoon because the kids were there."

In spite of the party time, one partygoer was too tired for additional festivities. Little Zuma was spotted snoozing in his car seat next to the birthday girl as the family rode away in their black Range Rover.

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Check out who else is painting the town in our Party Pics gallery.

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Thu., Aug. 21, 2008 5:45 PM PDT by Gina Serpe and Natalie Finn

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Love, angel, music, baby No. 2.

Gwen Stefani and Gavin Rossdale welcomed their second little prince today, E! News has confirmed.

Son Zuma Nesta Rock Rossdale was born Thursday at Los Angeles' Cedars-Sinai Medical Center, joining 2-year-old brother Kingston in the musically inclined couple's burgeoning brood.

The family's newest addition arrived at 12:46 p.m., weighing 8.5 pounds.

"Mother, baby and family are all happy and healthy," a rep for the couple said in a statement.

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Cox and Friends Stump for Skin Disease

Fri., Mar. 21, 2008 8:31 AM PDT by Sarah Hall

Courteney Cox is looking to her friends for help with her latest cause.

The Dirt star and her husband, David Arquette, have recruited a roster of famous folks, including Jennifer Aniston, to help them try to raise $1 million in two weeks for Epidermolysis Bullosa, a rare and debilitating skin condition that primarily affects children.

"EB is very personal to me, so I'm happy to be a part of this $1 million challenge," Cox said in a statement. "Now is such an important time to put the spotlight on EB and ensure that research can continue at a fast pace."

Aniston's ex, Brad Pitt, is also on board for the challenge, as are Gwen Stefani, Gavin Rossdale, Orlando Bloom, Kate Beckinsale, Rashida Jones, James Marsden and Eva Longoria Parker.

Cox and Arquette are heading up the effort as members of the honorary advisory board of the Epidermolysis Bullosa Medical Research Foundation. Aniston, Pitt, Rossdale and Stefani are also members.

Those affected by the condition break out in painful blisters after even minor trauma to the skin. Wounds may cover up to 75 percent of the body and never go away.

Few people who suffer from Epidermolysis Bullosa survive past the age of 30. As many as 100,000 Americans may have some form of the condition.