New Blood as Isaiah-Free Grey's Begins

Production has begun on the fourth, Isaiah Washington-free season of Grey's Anatomy–or is that Greys' Anatomy?

ABC announced Thursday that its top-rated medical melodrama resumed shooting this week following a tumultuous two-month hiatus. And while Washington's Dr. Preston Burke won't be roaming the halls of Seattle Grace this fall, there's a newbie in town ready to wreak some havoc.

Chyler Leigh has joined the cast as a series regular, scrubbing in as Lexie Grey, Meredith's (Ellen Pompeo) younger half-sister and the latest intern at Seattle Grace.

Leigh, 25, made a brief appearance at the close of last season, as the young woman who got a bit flirty with Derek Shepard (Patrick Dempsey), aka Dr. McDreamy, aka her sister's boyfriend, at a bar.

The spark between the two resulted in tension between Meredith and Derek, a theme that will likely continue in the coming season.

Prior to landing her gig as a Grey's regular, Leigh's résumé included starring roles on Fox's short-lived series Reunion and Girls Club, and recurring roles on ABC's The Practice and the WB's 7th Heaven. She also appeared in 2001's Not Another Teen Movie.

The North Carolina native is married to actor Nathan West, with whom she has a son and a daughter.

Leigh is the first new addition to Grey's since ABC announced last month that Washington's contract would not be renewed after a behind-the-scenes spat blew up into tabloid-friendly scandal.

So far the controversy hasn't hurt ratings. Last season, the series was the fourth-most popular show on television, averaging 18.7 million viewers.

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