Frasier Crane has reentered the building. Karen Filippelli, however, seems to have left it.

Such is the devastating blow Fox apparently dealt to fans of The Office Thursday morning while announcing its new fall schedule—which included Rashida Jones' sitcom The Rules for Starting Over, effectively relieving her of her Office duties.

However, the network offered plenty of consolation for fans of classic TV, and classic TV in the making, in the form of a resurgence of familiar faces in the prime-time lineup. The network unveiled 10 new series, four of which will have midseason debuts.

Among those slated to premiere in spring is Jones' sitcom, perhaps postponing her character's Dunder-Mifflin departure (we could find out for sure tonight, when the NBC show has its season finale). The Rules for Starting Over, costarring Craig Bierko, was created by the Farrelly brothers and revolves around a group of Boston-based thirtysomethings who are all suddenly single.

Meanwhile, one of the biggest-profile fall comebacks will be Kelsey Grammer, who will team up with another Emmy-winning sitcom alum, Everybody Loves Raymond's Patricia Heaton, for Back to You. The comedy series, which based on star power alone has already generated considerable buzz among advertisers, features Grammer as a TV anchorman who is fired from his glitzy Los Angeles gig and is forced to return to his old Pittsburgh station, where former coanchor and onetime love interest, Heaton, remains. Veteran funnyman Fred Willard also costars.

Back to You has been paired with 'Til Death, the only freshman series, comedy or drama, to be renewed by Fox for a sophomore season. In addition to forming a Wednesday night comedy block, the prime-time pairing will reunite, if only in terms of programming proximity, Heaton with fellow Raymond vet Brad Garrett.

Another of Fox's much hyped about new series is The Sarah Connor Chronicles, which is as much of a surprise pickup as ABC's acquisition of Private Practice. The hourlong drama, which will air on Sundays beginning next spring, stars 300's Lena Headey as the heroine of the Terminator franchise originally played by Linda Hamilton. The series will chronicle the plight of the mother and 15-year-old son John as they decide to stop running from their cyborg enemies and battle back in present-day Los Angeles.

To balance out its usual supply of sometimes dubious reality fare, Fox has opted to add some art-house credentials to its lineup, picking up New Amsterdam. Directed and executive produced by Chocolat and Cider House Rules helmer Lasse Hallström, the series follows an immortal New York homicide detective who earned his gift by saving a Native American girl as a young Dutch settler in New Amsterdam, which of course is present day Manhattan. The girl blessed/cursed him with everlasting life, which, it turns out, will really last once he finds true love...or the Nielsens slip.

The show will lead in to House on Tuesday nights until American Idol makes its comeback in January, at which point the series will make the move to Friday paired with Bones.

Fox has a more traditional police drama on the slate with K-Ville, with Anthony Anderson and Cole Hauser  as New Orleans cops forced to work in less than ideal conditions as their hometown continues to recover, quite slowly, from Hurricane Katrina.

That series will be teamed with Prison Break on Monday nights, eventually overtaking the serial's time slot in January, when 24 comes back.

Fox also announced three new reality offerings for the fall, including The Search for the Next Great American Band, which hopes to do for groups what American Idol did for individuals. The show, which is from the Idol brain trust and is getting tons of promotion during Idol, will air on Fridays.

Friday night will also be the home to Nashville, a docu-soap from the same people who made Kristin Cavallari, Lauren Conrad, Jason Wahler and the rest of their Laguna Beach ilk tabloid fodder. The series focuses on though attempting to make it big in the country music capital.

Rounding out the reality fare is Kitchen Nightmares, yet another vehicle featuring foul-mouthed culinary wiz Gordon Ramsay that first aired in the U.K.

In addition to the fall newbies, Fox also announced a midseason roster that includes The Rules for Starting Over and The Sarah Connor Chronicles and two more star-powered series, a legal drama and a family comedy.

Canterbury's Law stars ER alum Julianna Marguiles as a rebellious defense attorney—is there any other kind?—which has the bad luck to land Thursday at 9 p.m., opposite Grey's Anatomy.

The Return of Jezebel James stars indie darling Parker Posey and Six Feet Under's Lauren Ambrose as two estranged sisters who come together after one agrees to serve as a surrogate mother for the other. Lest it seem too saccharine, would-be viewers can take heart knowing the project comes from Gilmore Girls creators Dan and Amy Sherman-Palladino.

The final series getting the green light from Fox is Anchorman, set to debut this summer. The reality show will follow the real-life anchors and owner of Tyler, Texas' KYTX as the group attempts to raise the station's local news profile with the addition of a former Miss New York to their correspondent pack.

Fox preceded Thursday's lineup unveiling by announcing that 24 would return for two more seasons and MADtv would have a truncated run next season. The network previously announced the comebacks of  House, Bones, Prison Break, Are You Smarter Than a Fifth Grader?, Idol and The Simpsons. The latter, which celebrates its 400th episode this weekend, will be back for its 19th season on Sundays, along with the returning 'toons Family Guy, King of the Hill and American Dad.

Here's Fox's fall 2007-08 schedule, with new shows in bold.

Monday: Prison Break, K-Ville

Tuesday: New Amsterdam, House

Wednesday: Back to You, 'Til Death, Bones

Thursday: Are You Smarter Than a Fifth Grader?, Kitchen Nightmares

Friday: The Search for the Next Great American Band, Nashville

Saturday: Cops, America's Most Wanted: America Fights Back, MADtv, Talk Show with Spike Feresten

Sunday: The OT, The Simpsons, King of the Hill, Family Guy, American Dad

Here's Fox's spring 2008 schedule, with new shows in bold.

Monday: K-Ville/Prison Break, 24

Tuesday: American Idol, House

Wednesday: Back to You, The Return of Jezebel James, American Idol Results/'Til Death

Thursday: Are You Smarter Than a Fifth Grader?, Canterbury's Law

Friday: Bones, New Amsterdam

For the latest from the network upfronts, check out TV columnist Kristin Veitch's dispatches in Watch with Kristin.