Bono and Alicia Sing for the Kids

Bono and Alicia Keys are teaming up for the kids.

The artists have joined forces to record the single "Don't Give Up (Africa)," and will donate all proceeds to Keep A Child Alive, an organization that provides medicine to families infected with AIDS and the HIV virus.

The song will be available exclusively through iTunes Music Store, beginning on Tuesday.

Bono and Keys first performed the charity ballad together Nov. 3 in New York at the Black Ball, Keep A Child Alive's annual fundraiser, where Keys took the stage, playing her trademark piano and Bono sang via satellite from a remote location.

The song was originally recorded as "Don't Give Up" by Peter Gabriel and Kate Bush for Gabriel's 1986 album So.

"I love this song," Keys said in a statement. "And I love Bono. I really respect what he has done for Africa and how he has used his fame to do good in the world. I hope I can do half as much in my life.

"I believe AIDS is the most important issue we face, because how we treat the poor is a reflection of who we are as a people," Keys continued. "I urge everyone to recognize the extreme disaster Africa is facing and step up for the Motherland."

Both Keys, who serves as a global ambassador for Keep A Child Alive, and Bono have been longtime advocates in the battle against AIDS.

Apart from their charity work, both stars have been keeping busy with their day jobs.

Keys landed atop the charts last month with her stripped-down album Unplugged, featuring collaborations with artists such as Common, Mos Def, Damian Marley and Maroon 5's Adam Levine.

She also picked up four awards at the 2005 Grammys, including Best R&B Album for The Diary of Alicia Keys and Best R&B Song for "You Don't Know My Name."

Meanwhile, Bono is in the midst of a world tour in support of U2's How To Dismantle an Atomic Bomb, which earned the band a trio of Grammys in February, including Best Rock Performance and Best Rock Song for the iPod-pushing tune "Vertigo."

The Rock and Roll Hall of Famers are set to wrap up their extensive touring schedule in March 2006, with dates in Australia and New Zealand.

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