"You have a better chance of being struck by lightning than making it."

That's a tough thing to hear if you're trying to make it in Hollywood, and when Marki Costello says it, you'd better know it's the truth.

Granddaughter of Lou Costello (of famous comedy duo Abbot and Costello, daughter of a Beach Boys record producer, stepgranddaughter of Dean Martin and goddaughter of musician Terry Melcher, Marki Costello is the definition of Hollywood royalty.

The successful talent manager and celebrity coach spoke exclusively with E! News about growing up in Hollywood, the celebrities she has managed/worked with and what we'll be seeing on her upcoming show, The Drama Queen.

"I'm born and raised in this crazy, kooky town we call Hollywood," Marki revealed. "As my employees and clients say, 'Markiwood.'"

After being immersed in the entertainment world her whole life, Marki's mother told her to stay away from the entertainment business and stressed education. But after her mother passed away suddenly at age 48 from a brain aneurism, Marki dropped out of college.

"I was driving to school and it was a beautiful day out and there was no parking and I said, 'I'm going to the beach.' I think I was rebelling against my mom dying," Marki revealed. "But after about two months of going to the beach, I said, 'Well, what am I going to do with my life?' So I got a job working for Chuck Barris, and the rest was history."

The Drama Queen, Marki Costello

Barris, host of the The Gong Show and the creator of such classic game shows as The Newlywed Game and The Dating Game, met with Marki as a family favor and gave her some advice that would stick with her for her entire life.

"I remember him saying, 'Look kid, you can sit back and you can watch the wheel go round and round and round and say, Hmmm, should I get on? Is it going too fast? It looks slippery. It looks scary...Or, you just hop on the f--king wheel,'" Marki reminisced. "Literally, that saying, that moment, that statement from Chuck Barris made me go, 'I want to jump on the wheel. I want to jump on this opportunity in life.'"

Marki took a job with Chuck's company, learned production, got into casting shows and ultimately opened up her own company, Casting Entertainment Group.

After many years casting shows like the original The Bachelor and Temptation Island, Marki decided to get into talent management and created Creative Management Entertainment Group (CMEG).

"Almost 20 years later, I now have 26 clients, aka clients/brands," Marki detailed. "I now have 14 employees, a huge studio with a green screen, a camera, a teleprompter, three edit bays and a green room. Downstairs, I have a big classroom. We coach about 100 students a month that go through my media training."

Her experience in what Hollywood is looking for and the drama that occurs in "the business," are some of the things you'll be seeing on The Drama Queen.

"Jason Kennedy(E! News host) and I met when he was a junior at Miami University. Where Jason is today, is all solely because of me," Marki boasted. "I signed him, managed him, created his image, guided him, got him his job at E!, and to this day, eight years later, take care of his day-to-day."

"What the audience is going to see are those sort of transformations and what it takes to really be talent in 2013. It's a marathon, not a sprint," Marki continued. "We don't give away sitcoms at the Chevron gas station. There's a method to the madness of Hollywood and hard work pays off."

Marki's experience and client list proves she knows what she's talking about. She's worked with talent like CeeLo Green, Kelly Osbourne, Stacy Keibler and many more.

The Drama Queen, Marki Costello

"You'll see people that all want to be famous and some that are already famous. You'll get a real glimpse into what it's like in a successful, busy management office," Marki revealed. "There's nothing else like it on television."

The talent manager has worked with some very successful people, but how did these people get to where they are today? How do you make it in Hollywood?

"Show business is like the lottery. It's not based on who works the hardest, even though hard work pays off, it's about timing," Marki explains. "Timing. Luck. Talent. All of these things have to line up for you to walk through the gates of showbiz."

Tune in to the season premiere of The Drama Queen on Sunday, Nov. 17 at 11/10c on E!

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