Gotta love Leighton Meester and Blake Lively as East Siders Blair "Queen B" Waldorf and Serena "S" Van Der Woodsen on the CW's Gossip Girl. Nobody's hotter, onscreen or off. XOXO, ladies.
A virtual unknown when the series launched, Lost star Josh Holloway has become the face of the series. Tune in Jan. 21 for the season premiere to get a look at shirtless Sawyer in the jungle!
Neil Patrick Harris has had a banner year: His TV series How I Met Your Mother had series-high ratings (thanks in part to the Barney-Robin storyline), and his Web series Dr. Horrible was, well, legendary.
On Heroes, all roads lead back to Hayden Panettiere's Claire-Bear, especially now that she's been revealed as the Catalyst. Offscreen, Hayden puts just as much heroic effort into saving the whales.
Nobody does smartly sweet like John Krasinski and his TV alter ego, Jim Halpert. As charming and funny in real life as he is in Scranton, Pa., Office worker Krasinski makes our knees weak without any work at all.
The breakout big-screen star of Grey's Anatomy—only fellow castmember Patrick Dempsey has more movie mojo—Katherine Heigl is equally at home on TV, magazine covers and red carpets.
Thanks, England, for sending over Hugh Laurie. The roughneck doc he plays on Fox's House wouldn't be the same if Laurie weren't so inherently brilliant and charming. We owe you one.
Project Runway hostess and personality Heidi Klum makes success look easy—her natural charisma, warmth and unscripted sense of humor are as glamorous as any of the clothes designed for her hit reality show.
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