As Sheen's meltdown continues—he grants a slew of interviews to outlets ranging from E! to Good Morning America to the Today Show, among others—the actor's longtime publicist, Stan Rosenfield, calls it quits. But Sheen responds by telling TMZ, "He's not allowed to quit, so you're fired."
John Stamos denies rumors via Twitter that he's been tapped to replace Sheen on Two and a Half Men. However, sources tell E! News exclusively that CBS head honcho Les Moonves was spotted chatting with Stamos at a pre-Oscar event in Hollywood the next day.
After Sheen rips Two and a Half Men boss Chuck Lorre on the Alex Jones radio show, referring to him as "Chaim Levine"—which the Anti-Defamation League deems "borderline anti-Semitism"—CBS and Warner Bros. cancel production of the hit show for the rest of the season.
Two and a Half Men's cocreator and executive producer Chuck Lorre speaks out about the Sheen drama via vanity card. Sentiments Lorre expressed include, "If Charlie Sheen outlives me, I'm gonna be really pissed," and "No matter how hard he partied, he could never escape that simple fact - inside, dead."
A Los Angeles Superior Court judge signs off on Sheen and Mueller's divorce, but it won't become official until May 2—per California law a divorce isn't finalized until six months after a party files the paperwork. However, just week's later, Mueller and the twins are living with the star while the threesome are in between homes.
Third time's a charm? Sheen voluntarily checks himself into an "undisclosed rehabilitation center," reads a statement from his rep. CBS also issues a releasing stating that his hit show, Two and a Half Men, is on production hiatus.
After a reported 36-hour bender at his Mulholland home with porn stars, Sheen is rushed to Los Angeles' Cedars-Sinai Medical Center in an ambulance for what his rep says is "severe abdominal pain"—he is released later the same day.
During the Television Critics Association panel, a CBS executive expresses a "high level of concern" for the actor.
Charlie misses a day of work on Two and a Half Men after spending the weekend at a porn convention in Las Vegas. His rep attributes his absence to an "ear infection."
The thrice-married star formally files for divorce from Brooke Mueller after, um, two and a half years of marriage. The couple are currently ironing out custody of their twin boys, Max and Bob, born March 2009.
The actor is taken from New York's Plaza Hotel to the hospital and later questioned by police after reportedly trashing his room. Porn star Capri Anderson, who was with him at the time of the disturbance, goes public. Sheen is hospitalized after the incident for what his rep calls "an allergic reaction to some medication." Anderson later threatens to sue the actor for battery and false imprisonment and Sheen, in turn, threatens to file a countersuit agins Anderson for extortion. Neither party files, though, and they reportedly settle out of court.
Hollywood's bad boy pleads guilty to misdemeanor third-degree assault for the Christmas attack on wife Brooke Mueller. He is ordered to spend 30 days in rehab, go to domestic abuse counseling and placed on probation.
Vehicles belonging to Sheen are stolen from his home and driven off a cliff, not once but twice. No suspects are ever identified.
Taking a leave of absence from his hit show, the Two and a Half Men star checks himself into rehab for what his rep refers to as a "preventative measure."
Sheen is arrested and booked on Christmas Day in Aspen, Colo., after wife Brooke Mueller alleges he grabbed her throat while holding a knife. The actor spends eight hours in jail before being released on bail.
A pregnant Denise Richards files for divorce after less than three years of matrimony. She later claims that Sheen abused drugs and alcohol and threatened her with violence while they were married. Richards has sole custody of their daughters, Sam and Lola.
It's back to rehab for the embattled actor after he's hospitalized for a near-fatal overdose—Charlie's own father, Martin Sheen, reports his son's parole violation.
The star is arrested for assaulting then-girlfriend Brittany Ashland. He pleads no contest a year later to the assault charge and is sentenced to two years' probation.
Testifying at Hollywood Madam Heidi Fleiss' trial, Charlie admits to paying more than $50,000 for services from prostitutes.
Sheen enters rehab for the first time for alcohol addiction. His engagement to Kelly Preston ends later that year following reports he accidently shot her in the arm.
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